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Advillin-Cre-ER(T2)

An inducible Cre transgenic mouse useful for analysing gene function in sensory neurons

2 licensing options
BMI-1 transduced basal epithelial cells

BMI-1 transduced basal epithelial cells from normal healthy donors. Nasal in origin.

2 licensing options
Emx1-iCre

This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes, in the neuroepithelium of the embryonic cerebral cortex.

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Gsh2-iCre

This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes, in the neuroepithelium of the embryonic subcortical telencephalon.

2 licensing options
MIO-M1 cells

Spontaneously immortalized human Müller glia cell line

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Msx3-iCre

This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes in the dorsal spinal cord neuroepithelium.

2 licensing options
Pdgfb-CreER

Pdgfb-CreER mice

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Pdgfra-CreER(T2)

Pdgfra-CreER(T2) transgenic mice

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Sox10-GFP/tdTom

This is a dual-reporter mouse line Sox10-lox-eGFP-STOP-lox-tdTomato (referred to as Sox10-GFP/td-Tom), designed for studies of oligodendrocyte (OL) lineage cells and generated by PAC transgenesis. Recombination under the influence of Cre leads to the expression of tdTomato instead of GFP. A majority of OL lineage cells (95%) in the corpus callosum expresses the transgene.

2 licensing options
Sox10-iCreER(T2)

Sox10-iCreERT2. Codon-improved version of CreERT2 expressed under the transcriptional control of Sox10 sequences in a PAC. This is designed to express in myelinating cells of the CNS and PNS (oligodendrocytes and Schwann cells, respectively) following tamoxifen administration. Pre-natal tamoxifen might also induce expression in migratory neural crest cells, although this has not been tested.

1 licensing option