Pdgfb-CreER

Pdgfb-CreER mice
Technology No. 88-050

Note: supply of these mice from University College London will include one male and two females as a package. Only one package will be supplied for each approved request.

Pdgfb-CreER mice express tamoxifen inducible Cre-recombinase in endothelial cells of the microvasculature. They have been made by using a PAC containing the Pdgfb gene for transgenesis (random integration). The ORF of the Pdgfb gene was replaced with the coding sequence for the fusion protein iCreERT2 (iCre stands for improved Cre), followed by an IRES and the coding sequence for EGFP  (See PMID: 18257043 for more details).

 

 


  • swap_vertical_circlelibrary_booksReferences (1)
    1. Fruttiger, Hodivala-Dilke, Chambon, Jadeja, Kostourou, Claxton (2008), Efficient, inducible Cre-recombinase activation in vascular endothelium, Genesis, 46(2), 74-80
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    Pdgfb-CreER mice protocol.doc
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Licence - Other Use
For commercial use.

Term: perpetual

Price per 1 unit:
TBD

Material Transfer Agreement
For non-commercial research by non-profit organisations

Term: perpetual

Price per 1 unit:
£0.00 excl. VAT