Advillin-Cre-ER(T2)
An inducible Cre transgenic mouse useful for analysing gene function in sensory neurons
Emx1-iCre
This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes, in the neuroepithelium of the embryonic cerebral cortex.
Gsh2-iCre
This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes, in the neuroepithelium of the embryonic subcortical telencephalon.
Msx3-iCre
This line is useful for driving Cre-mediated recombination of reporter lines, or for deleting floxed genes in the dorsal spinal cord neuroepithelium.
Pdgfb-CreER
Pdgfb-CreER mice
Pdgfra-CreER(T2)
Pdgfra-CreER(T2) transgenic mice
Sox10-GFP/DTA transgenic mice
This line, Sox10-lox-eGFP-polyA-lox-DTA (referred to as Sox10-GFP/DTA) was designed for studies of oligodendrocyte (OL) lineage cells but, with an appropriate Cre driver, could be used for any Sox10-expressing cell population (e.g. Schwann cells). In the absence of Cre, GFP labels the entire OL lineage (as well as other cells outside the CNS that express Sox10). In the presence of Cre, DTA expression results in death of all Cre/Sox10-expressing cells.
Sox10-GFP/tdTom
This is a dual-reporter mouse line Sox10-lox-eGFP-STOP-lox-tdTomato (referred to as Sox10-GFP/td-Tom), designed for studies of oligodendrocyte (OL) lineage cells and generated by PAC transgenesis. Recombination under the influence of Cre leads to the expression of tdTomato instead of GFP. A majority of OL lineage cells (95%) in the corpus callosum expresses the transgene.