You are not signed in.
My basket (no items)
Sign-in
Express Licensing Express licensing from UCL Business
  • DESCRIPTION
  • FILES (1)
  • REFERENCES (1)
  • SUPPORT

We used a 120 kb NotI fragment of the Sox10 genomic PAC (RP21-427-F18), which includes 60 kb upstream and 50 kb downstream of Sox10.  The genomic region spanning exons 3–5 was replaced by loxP-eGFP-polyAx4-loxP-tdTomato-frt-CmR-frt by homologous recombination in E. coli. The CmR cassette was removed by transient activation of Flp recombinase with arabinose.  Founders were generated by pronuclear injection.  Several founders transmitted the transgene in roughly Mendelian ratios and expressed GFP strongly in the expected pattern.  One male founder was used to establish a line for further study.  For further details of the line and its use see Tripathi et al. (2011).  Dorsally- and ventrally-derived oligodendrocytes have similar electrical properties but myelinate preferred tracts. J. Neurosci. 31, 6809-6819. http://www.ncbi.nlm.nih.gov/pubmed/21543611.

  

 

 

Sox10-GFP/tdTom

Sox10 dual reporter (green fluorescent protein/ tandem-duplicated Tomato).Sox10-lox-GFP-STOP-lox-tdTomato mice.

OPTIONS
Please check carefully that the terms you select correspond to your intended use of the product.

Material Transfer Agreement 2.01

For non-commercial research by non-profit organisations

View Terms

Further details
Term: perpetual (does not require renewal)
Seats: n/a

Price excl. VAT: Free of charge

Licence - Other Use 1.00

View Terms

Further details
Term: perpetual (does not require renewal)
Seats: n/a

Price excl. VAT: P.O.A. (price on application)

Please contact us before adding this licence to your basket.