Note: supply of these mice from University College London will include one male and two females as a package. Only one package will be supplied for each approved request.
Pdgfb-CreER mice express tamoxifen inducible Cre-recombinase in endothelial cells of the microvasculature. They have been made by using a PAC containing the Pdgfb gene for transgenesis (random integration). The ORF of the Pdgfb gene was replaced with the coding sequence for the fusion protein iCreERT2 (iCre stands for improved Cre), followed by an IRES and the coding sequence for EGFP (See PMID: 18257043 for more details).
Please note that an approved licence is required before commercial files related to this product can be downloaded. Such files are indicated by .
To request the mice, please check the box for the relevant licensing option in the left column, click the 'Add Licence(s) to Basket' button below and checkout from 'My Basket' in the top right corner of the page.
What happens after I submit a request?
Before the mice can be dispatched, approval for this material and the relevant licence agreement is required. In the checkout process, you will be asked to provide details of the legal representative of your organisation who is authorised to approve material transfer/ licence agreements on behalf of your organisation. Please have this information ready before submitting a request. E-lucid will contact your legal representative directly for approval. Once all appropriate approvals have been obtained, we will contact you for shipping of the mice.