Spontaneoulsy immortalized human Müller glia cell line. Cells grow indefinitely under adherent conditions in the presence or absence of extracellular matrix proteins. Optimal medium for cell growth: DMEM medium containing high glucose and stable glutamine, supplemented with 10% foetal bovine serum.
Under normal culture conditions, MIO-M1 express markers of mature Müller cells, including cellular retinaldehyde binding protein [CRALBP], glutamine synthetase, vimentin and epidermal growth factor receptor-[EGF-R].
The cells are NOT intended for Stem cell Research.
Size: Cells are shipped growing in 25cm2 flasks.
If you require more than one unit, please contact us before placing an order.
For commecial use, please contact us to discuss licensing options.
Full acknowledgement of the source of the MIO-M1 cells must be given in all relvant publications and presentations of research results.
The following statement must be included in all publications and the accompanying reference must be cited:
'The human Müller cell line Moorfields/Institute of Ophthalmology- Müller 1 (MIO-M1) was obtained from the UCL Institute of Ophthalmology, London, UK.'
The reference is:
'Limb GA, Salt TE, Munro PMG, Moss SE and Khaw PT. (2002) In vitro characterization of a spontaneously immortalized human Müller cell line (MIO-M1). Investigative Ophthalmology and Visual Science, 43: 864-869'
To initiate your order, please select the appropriate licence, found on the left-hand side of this page and click ‘add to basket’. Once added proceed through checkout to complete your request.
MTAs require agreement between all the parties involved in supplying and receiving a product. This cannot happen instantaneously but is a controlled process, managed through XIP and should not take longer than 10 business days in ordinary circumstances.
For further information, visit our FAQ section.
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To request this cell line, please check the box for the relevant licensing option in the left column, click the 'Add Licence(s) to Basket' button below and checkout from 'My Basket' in the top right corner of the page
Before the cell line can be dispatched, approval for this request and the relevant licence agreement is required. In the checkout process, you will be asked to provide details of the legal representative of your organisation who is authorised to approve material transfer/ licence agreements on behalf of your organisation. Please have this information ready before submitting a request. E-lucid will contact your legal representative directly for approval. Once all appropriate approvals have been obtained, we will contact you for shipping of the cell line.