A bacterial artificial chromosome (BAC) transgenic line that expresses tamoxifen-inducible Cre recombinase in Fgfr3-expressing cells throughout the body, including astrocytes in the CNS, neural stem cells in the SVZ, hippocampus and spinal cord ependymal zone, and inner ear cells (organ of Corti).
Young, K.M., Mitsumori, T., Pringle, N., Grist, M., Kessaris, N. and Richardson, W.D. (2010). An Fgfr3-iCreERT2 transgenic line for studies of astrocytes and neural stem cells in the mouse CNS. Glia 58, 943-953.
Anttonen, T., Kirjavainen, A., Belevich, I., Laos, M., Richardson, W.D., Jokitalo, E., Brakebusch, C. and Pirvola, U. (2012). Cdc42-dependent structural development of auditory supporting cells is required for wound healing in adulthood. Sci. Rep. 2, 978. doi: 10.1038/srep00978
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