Genetically Modified Organisms
Subcategories of "Biological Materials"
Advillin-Cre-ER(T2) mice
An inducible Cre transgenic mouse useful for analysing gene function in sensory neurons
An immortalised Lewis rat brain vascular endothelial cell line
GPNT was derived from the immortalised rat brain endothelial cell line GP8 by lipofectin-mediated transfection with a vector containing the puromycin resistance gene. GPNT exhibits a non-transformed phenotype.
Dll4 flox transgenic mice on a Bl6 background
These transgenic mice have had LoxP sites inserted into the Dll4 gene and thus Dll4 in these mice can be inducibly deleted via the use of cre technology.
fibroblast growth factor receptor 3 - improved CreER(T2)
A bacterial artificial chromosome (BAC) transgenic line that expresses tamoxifen-inducible Cre recombinase in Fgfr3-expressing cells throughout the body, including astrocytes in the CNS, neural stem cells in the SVZ, hippocampus and spinal cord ependymal zone, and inner ear cells (organ of Corti).
HIV-1 NL4.3BaL CA N74D INT D116N plasmid
Full length molecular clone of HIV-1 capsid mutant N74D, Intergrase mutant D116N.
HIV-1 NL4.3BaL CA N74D plasmid
Full length molecular clone of HIV-1 capsid mutant N74D.
HIV-1 NL4.3BaL CA N74D RT D185E plasmid
Full length molecular clone of HIV-1 capsid mutant N74D, RT mutant D185E.
HIV-1 NL4.3BaL CA P90A INT D116N plasmid
Full length molecular clone of HIV-1 capsid mutant P90A, Intergrase mutant D116N.
HIV-1 NL4.3BaL CA P90A plasmid
Full length molecular clone of HIV-1 capsid mutant P90A.
HIV-1 NL4.3BaL CA P90A RT D185E plasmid
Full length molecular clone of HIV-1 capsid mutant P90A, RT mutant D185E.
HIV-1 NL4.3BaL wt plasmid
Full length molecular clone of HIV-1 NL4.3 BaL.
Pdgfra-CreER(T2) transgenic mice
Sox10 dual reporter (green fluorescent protein/ tandem-duplicated Tomato).Sox10-lox-GFP-STOP-lox-tdTomato mice.
This is a dual-reporter mouse line Sox10-lox-eGFP-STOP-lox-tdTomato (referred to as Sox10-GFP/td-Tom), designed for studies of oligodendrocyte (OL) lineage cells and generated by PAC transgenesis. Recombination under the influence of Cre leads to the expression of tdTomato instead of GFP. A majority of OL lineage cells (95%) in the corpus callosum expresses the transgene.
Sox10-iCreER(T2): Codon-improved version of CreER(T2) expressed under the transcriptional control of Sox10 sequences in a PAC.
Sox10-iCreERT2. Codon-improved version of CreERT2 expressed under the transcriptional control of Sox10 sequences in a PAC. This is designed to express in myelinating cells of the CNS and PNS (oligodendrocytes and Schwann cells, respectively) following tamoxifen administration. Pre-natal tamoxifen might also induce expression in migratory neural crest cells, although this has not been tested.
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